Carbamazepine is known to produce the side effect of euphoria. As such, it lends itself to being a drug of abuse, particularly in\nthe adolescent population. This retrospective study evaluated carbamazepine abuse, treatment course, and associated morbidity\nin Chinese adolescents. The median dose of carbamazepine resulting in overdose was 2,000mg (800ââ?¬â??5,000). Patients were largely\nfrom urban-rural fringe areas (76.47%, 52.94%) with school performance within the last 1/3 range and (52.94%) unsupervised by\nparents. 35.29% experienced an obvious sense of euphoria. All patients had nervous system symptoms, 6 (35.29%) cases developed\ncoma (GCS < 8), and 5 (29.41%) cases experienced convulsion. Four cases were treated with hemodialysis. The incidence rate in\nyoung patients with repeat carbamazepine use and without the supervision of parents was higher than that in first-time users (5/7\nversus 4/10), but the difference was not significant.The toxic dose of repeat users was 3428 Ã?± 1035mg, significantly higher than that\nof 1470 Ã?± 646mg in first-time users (
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